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How Fat Loss Works: The Science Behind Shedding Body Fat

John Schaefer | Mar 26, 2025
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How Fat Loss Works: The Science Behind Shedding Body Fat

Fat loss is often oversimplified as “eat less, move more.” While that statement isn’t entirely wrong, it leaves out critical details about how your body burns fat, where your energy comes from, and what truly drives sustainable progress. If you’ve ever wondered why some diets work and others fail, or why fat loss can feel so slow, understanding the science behind fat loss can make all the difference.

Let’s break it down so that you can take a smarter, more effective approach to your goals.

The Basics of Fat Loss: Calories In vs. Calories Out

At the core of fat loss is energy balance—the relationship between the calories you consume and the calories your body burns. If you consistently consume more calories than you burn, the excess energy is stored as fat. On the flip side, if you burn more calories than you consume, your body taps into stored fat for energy, leading to fat loss.

This is known as a caloric deficit and is the single most important factor in fat loss. No diet, exercise plan, or supplement will override the need for a calorie deficit.

But while the concept of “eat less, move more” is technically true, it doesn’t mean fat loss is just about extreme restriction. The way your body burns calories—and whether it burns carbs or fat—depends on how you fuel it and how you move.

How Your Body Uses Energy: The Fueling System

Your body primarily relies on three macronutrients for energy: carbohydrates, fats, and proteins. Each plays a role in your metabolism, but they don’t all get used the same way.

  • Carbohydrates – The body’s preferred and most immediate energy source. When you eat carbs, they are broken down into glucose and either used for energy or stored as glycogen in your muscles and liver.
  • Fat – Your long-term energy reserve. When your body isn’t getting enough immediate energy from food, it turns to stored fat for fuel.
  • Protein – Primarily used for muscle repair and bodily functions, protein is not a major energy source unless your body is in starvation mode.

Think of your body like a wood-burning stove:

  • Carbs are like kindling—they burn quickly and provide immediate energy.
  • Fat is like a slow-burning log—it provides steady, long-lasting energy, but only once the kindling burns out.

Your body burns carbs first, then shifts to burning fat when glycogen stores are low. This is why fasting, low-carb diets, and endurance exercise can increase fat burning—they deplete glycogen faster, forcing your body to rely on fat for fuel.

The Science of Fat Burning: Lipolysis & Fat Oxidation

Fat loss happens in two key steps:

  1. Lipolysis – Your body breaks down fat stores into fatty acids.
  2. Fat Oxidation – These fatty acids are transported to the muscles and burned for energy.

However, fat isn’t burned unless your body needs to use it. If you’re eating more calories than you burn, your body has no reason to dip into fat stores. This is why exercise and diet work together—exercise increases calorie burn, while a caloric deficit forces your body to rely on fat for fuel.

One key factor in this process is hydration. Your body requires water to effectively break down fat. Without proper hydration, fat loss becomes inefficient, making it harder to burn stored fat.

Why Strength Training is Crucial for Fat Loss

Many people focus only on cardio for fat loss, but strength training is just as—if not more—important.

Muscle is metabolically active, meaning it burns calories even at rest. The more muscle you have, the higher your resting metabolic rate (RMR), meaning your body naturally burns more calories throughout the day—even while you sleep.

Here’s why strength training matters:

  • It preserves muscle while in a calorie deficit, preventing the metabolism from slowing down.
  • It increases afterburn effect (EPOC), meaning your body burns calories for hours post-workout.
  • More muscle = higher daily calorie burn without needing extra cardio.

The Role of Cardio in Fat Loss

While strength training is crucial, cardio still has its place. Different types of cardio impact fat loss in different ways:

  • Low-Intensity Steady-State Cardio (LISS) – Walking, biking, or light jogging at a steady pace primarily burns fat for fuel while keeping stress low.
  • High-Intensity Interval Training (HIIT) – Short bursts of intense effort burn both carbs and fat, increase calorie burn for hours after exercise, and are highly time-efficient.

One of the best ways to maximize fat burning is Zone 2 training—moderate-intensity exercise that keeps your heart rate at 60-70% of its max. This type of training trains your body to burn fat more efficiently while improving endurance and overall metabolic health.

Common Myths About Fat Loss

There’s a lot of misinformation out there about fat loss. Let’s set the record straight on a few common myths:

  • “Eating fat makes you fat.” Not true. Dietary fat does not directly cause fat gain—only excess calories do. Healthy fats from sources like avocado, nuts, and olive oil are essential for hormone balance and satiety.
  • “You need to eat six small meals a day to boost metabolism.” Meal frequency doesn’t matter as much as total calorie intake. Some people do well with multiple small meals, while others prefer larger meals in a shorter window (like intermittent fasting).
  • “Low-carb diets are the only way to lose fat.” While low-carb diets can help some people manage appetite and blood sugar, fat loss still comes down to a calorie deficit. You can lose fat while eating carbs, as long as you stay in that deficit.

How to Make Fat Loss Sustainable

Short-term fixes don’t work. Sustainable fat loss comes from long-term habits.

  1. Strength train at least 2-3 times per week to preserve muscle and boost metabolism.
  2. Create a calorie deficit by eating slightly fewer calories than you burn—without extreme restriction.
  3. Prioritize protein to keep you full and support muscle retention. Aim for 0.6-1g per pound of goal body weight.
  4. Move more throughout the day. Walking 10,000 steps per day can significantly increase calorie burn without added stress.
  5. Stay hydrated. Water is essential for fat breakdown and overall health.

The Bottom Line: How Fat Loss Actually Works

Fat loss isn’t about quick fixes—it’s about consistent, strategic effort over time. It happens when you:

  • Consume fewer calories than you burn (caloric deficit).
  • Use up stored glycogen so your body taps into fat for fuel.
  • Strength train to preserve muscle and increase metabolism.
  • Incorporate cardio to support energy balance and heart health.
  • Prioritize protein, hydration, and movement for sustainability.

It’s not about perfection. Small, daily improvements add up over time. Focus on building habits that fit your life, and results will follow.

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